test_locuslink
Testing Bio.LocusLink on LL_block


record 0

ACCNUM:
             ACCNUM:
                AC010642|9929687|na|43581|41119
             TYPE:
                g

             ACCNUM:
                AA484435|2213248|na|na|na
             TYPE:
                m

             ACCNUM:
                AF414429|15778555|na|na|na
             PROT:
                AAL07469|15778556
             TYPE:
                m

             ACCNUM:
                AI022193|3239546|na|na|na
             TYPE:
                m

             ACCNUM:
                AK055885|16550723|na|na|na
             TYPE:
                m

             ACCNUM:
                AK056201|16551539|na|na|na
             TYPE:
                m

             ACCNUM:
                T80683|703568|na|na|na
             TYPE:
                m

             ACCNUM:
                W25099|1302954|na|na|na
             TYPE:
                m


ALIAS_SYMBOL:
            A1B
            ABG
            GAB

ASSEMBLY:
        AF414429,AK055885,AK056201
CDD:
            Immunoglobulin C-2 Type|smart00408|104|na|4.466900e+01
            Immunoglobulin C-2 Type|smart00408|104|6.130e-06|44.669

CHR:
        19
COMP:
            10090|A1bg|na|na|117586|19|A1BG|ncbi_mgd
            10090|A1bg|7|7  cM|117586|19|A1BG|ncbi_mgd

CONTIG:
        NT_011104.11|20544099|na|1555258|1566315|+|19
DB:
             DB_DESCR:
                GeneCards
             DB_LINK:
                http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?A1BG


EVID:
        supported by alignment with mRNA
LINK:
            http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=373554
            http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?locusId=1
            http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=1[loc]
            http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:119638
            http://www.ensembl.org/Homo_sapiens/contigview?geneid=NM_130786
            http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg12&position=NM_130786

LOCUSID:
        1
LOCUS_CONFIRMED:
        yes
LOCUS_TYPE:
        gene with protein product, function known or inferred
MAP:
        19q13.4|RefSeq|C|
MAPLINK:
        default_human_gene|A1BG
NM:
        NM_130786|21071029|na
NP:
        NP_570602|21071030
OFFICIAL_GENE_NAME:
        alpha-1-B glycoprotein
OFFICIAL_SYMBOL:
        A1BG
OMIM:
        138670
ORGANISM:
        Homo sapiens
PMID:
        8889549,3458201,2591067
PREFERRED_PRODUCT:
        alpha 1B-glycoprotein
PRODUCT:
        alpha 1B-glycoprotein
STATUS:
        REVIEWED
STS:
            RH65092|-|10673|na|na|epcr
            WI-16009|-|52209|na|na|epcr
            G59506|-|136670|na|na|epcr

SUMMARY:
        Summary: The protein encoded by this gene is a plasma glycoprotein of unknown function. The protein shows sequence similarity to the variable regions of some immunoglobulin supergene family member proteins.
UNIGENE:
        Hs.373554
XM:
        XM_058938|20544041|na
XP:
        XP_058938|17482319|na


record 1

ACCNUM:
             ACCNUM:
                X68728|450521|na|na|na
             PROT:
                CAA48670|825615
             TYPE:
                g

             ACCNUM:
                Z11711|24760|na|na|na
             PROT:
                CAA77774|24761
             TYPE:
                g

             ACCNUM:
                M11313|177869|na|na|na
             PROT:
                AAA51551|177870
             TYPE:
                m

             ACCNUM:
                M36501|177871|na|na|na
             PROT:
                AAA51552|177872
             TYPE:
                m


ASSEMBLY:
        M11313
CDD:
            Ependymins|EPEND|86|na|3.773540e+01
            Alpha-2-macroglobulin family|pfam00207|2501|na|9.679920e+02
            Alpha-2-macroglobulin family N-terminal region|pfam01835|1889|na|7.322500e+02
            Alpha-2-macroglobulin family|pfam00207|2449|0.000e+00|947.962
            Alpha-2-macroglobulin family N-terminal region|pfam01835|1931|0.000e+00|748.429

CHR:
        12
COMP:
            10090|A2m|6|6 62.00 cM|11287|12|A2M|ncbi_mgd
            10090|A2m|6|6 62.00 cM|11287|12|A2M|ucsc_mgd

CONTIG:
        NT_009702.9|20554950|na|365512|413776|+|12
DB:
             DB_DESCR:
                GeneCards
             DB_LINK:
                http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?A2M


EVID:
        supported by alignment with mRNA
EXTANNOT:
            organismal role|CNS-specific functions|NR|Proteome|1281457
            biochemical function|Inhibitor or repressor|NR|Proteome|1281457

GO:
            molecular function|protein carrier|NR|GO:0008320|Proteome|na
            molecular function|proteinase inhibitor|NR|GO:0004866|Proteome|na
            biological process|intracellular protein traffic|NR|GO:0006886|Proteome|na

GRIF:
            11811950|Differential binding to ldl receptor related protein
            11823454|distinct binding sites mediate interaction with beta-amyloid peptide and growth factors

LINK:
            http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=74561
            http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?locusId=2
            http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=2[loc]
            http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:119639
            http://www.uwcm.ac.uk/uwcm/mg/search/119639.html
            http://www.ensembl.org/Homo_sapiens/contigview?geneid=NM_000014
            http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg12&position=NM_000014

LOCUSID:
        2
LOCUS_CONFIRMED:
        yes
LOCUS_TYPE:
        gene with protein product, function known or inferred
MAP:
        12p13.3-p12.3|<a href="http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:119639">HUGO</a>|C|
MAPLINK:
        default_human_gene|A2M
NM:
        NM_000014|6226959|na
NP:
        NP_000005|4557225
OFFICIAL_GENE_NAME:
        alpha-2-macroglobulin
OFFICIAL_SYMBOL:
        A2M
OMIM:
        103950
ORGANISM:
        Homo sapiens
PHENOTYPE:
             PHENOTYPE:
                Alzheimer disease, susceptibility to
             PHENOTYPE_ID:
                103950

             PHENOTYPE:
                Emphysema due to alpha-2-macroglobulin deficiency
             PHENOTYPE_ID:
                103950


PMID:
        11823454,11811950,2581245,2408344,1707161,1370808,1281457
PREFERRED_PRODUCT:
        alpha 2 macroglobulin precursor
PRODUCT:
        alpha 2 macroglobulin precursor
STATUS:
        REVIEWED
STS:
            SGC31674|12|40245|na|na|epcr
            RH11157|12|46849|na|na|epcr
            G44356|12|95143|na|seq_map|epcr

SUMFUNC:
        Alpha-2-macroglobulin; protease inhibitor, binds/aids in cellular internalization of proteins|Proteome
SUMMARY:
        Summary: Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
UNIGENE:
        Hs.74561
XM:
        XM_006925|18580498|na
XP:
        XP_006925|17455493|na


record 2

ACCNUM:
             ACCNUM:
                M24415|187575|na|177|2881
             TYPE:
                g


CHR:
        12
DB:
             DB_DESCR:
                GeneCards
             DB_LINK:
                http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?A2MP


LINK:
        http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:128103
LOCUSID:
        3
LOCUS_CONFIRMED:
        yes
LOCUS_TYPE:
        pseudogene
MAP:
        12p13.3-p12.3|<a href="http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:128103">HUGO</a>|C|
MAPLINK:
        default_human_cyto|A2MP
OFFICIAL_GENE_NAME:
        alpha-2-macroglobulin pseudogene
OFFICIAL_SYMBOL:
        A2MP
ORGANISM:
        Homo sapiens
PMID:
        2478422
STATUS:
        REVIEWED


record 3

CHR:
        11
DB:
             DB_DESCR:
                GeneCards
             DB_LINK:
                http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?AA


LINK:
        http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:568984
LOCUSID:
        8
LOCUS_CONFIRMED:
        yes
LOCUS_TYPE:
        gene with protein product, function known or inferred
MAP:
        11p15|<a href="http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:568984">HUGO</a>|C|
MAPLINK:
        default_human_cyto|AA
OFFICIAL_GENE_NAME:
        atrophia areata, peripapillary chorioretinal degeneration
OFFICIAL_SYMBOL:
        AA
OMIM:
        108985
ORGANISM:
        Homo sapiens
PHENOTYPE:
             PHENOTYPE:
                Atrophia areata
             PHENOTYPE_ID:
                108985


PMID:
        7795606


record 4

ACCNUM:
             ACCNUM:
                AF008204|2618821|na|na|na
             PROT:
                AAB84384|2258431
             TYPE:
                g

             ACCNUM:
                AF032677|2641552|na|na|na
             PROT:
                AAB86878|2641553
             TYPE:
                g

             ACCNUM:
                AF032678|2641554|na|na|na
             PROT:
                AAB86879|2641555
             TYPE:
                g

             ACCNUM:
                AF067408|3265061|na|na|na
             PROT:
                AAC24707|3265062
             TYPE:
                g

             ACCNUM:
                AF071552|3265151|na|na|na
             PROT:
                AAC24712|3265152
             TYPE:
                g

             ACCNUM:
                AF082903|3435297|na|na|na
             PROT:
                AAD13343|3435298
             TYPE:
                g

             ACCNUM:
                AF082904|3435299|na|na|na
             PROT:
                AAC32388|3435300
             TYPE:
                g

             ACCNUM:
                U80835|2245375|na|na|na
             PROT:
                AAB62398|2245376
             TYPE:
                g

             ACCNUM:
                X17059|34993|na|na|na
             PROT:
                CAA34905|34994
             TYPE:
                g

             ACCNUM:
                BC013732|16975545|na|na|na
             PROT:
                AAH13732|16975546
             TYPE:
                m

             ACCNUM:
                D90041|219413|na|na|na
             PROT:
                BAA14095|219414
             TYPE:
                m


ALIAS_PROT:
            arylamine N-acetyltransferase-1
            arylamide acetylase 1 (N-acetyltransferase 1)

ALIAS_SYMBOL:
        AAC1
ASSEMBLY:
        BC013732
CDD:
        N-acetyltransferase|pfam00797|1030|na|4.056250e+02
CHR:
        8
COMP:
            10090|Nat1|8|8 31.00 cM|17960|8|NAT1|ncbi_mgd
            10090|Nat1|8|8 31.00 cM|17960|8|NAT1|ucsc_mgd
            10090|U35886|8|8 14135.38 cR|17961|8|AW390667|natgen_paper

CONTIG:
        NT_030737.3|20541522|na|1907807|1921012|+|8
DB:
             DB_DESCR:
                GeneCards
             DB_LINK:
                http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?NAT1

             DB_DESCR:
                Arylamine N-Acetyltransferase Nomenclature
             DB_LINK:
                http://www.louisville.edu/medschool/pharmacology/NAT.html


ECNUM:
        2.3.1.5
EVID:
        supported by alignment with mRNA
EXTANNOT:
            cellular role|Other metabolism|E|Proteome|10908296
            biochemical function|Transferase|E|Proteome|10908296

GO:
        molecular function|arylamine N-acetyltransferase|E|GO:0004060|Proteome|10908296
GRIF:
            11955676|paclitaxel is an uncompetitive inhibitor to arylamine N-acetyltransferase (NAT) enzyme
            11955677|paclitaxel affected human leukemia HL-60 cells arylamine N-acetyltransferase (NAT) activity and DNA-2-aminofluorene adduct formation.

LINK:
            http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=155956
            http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?locusId=9
            http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=9[loc]
            http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:125364
            http://www.ensembl.org/Homo_sapiens/contigview?geneid=NM_000662
            http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg12&position=NM_000662

LOCUSID:
        9
LOCUS_CONFIRMED:
        yes
LOCUS_TYPE:
        gene with protein product, function known or inferred
MAP:
        8p23.1-p21.3|<a href="http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:125364">HUGO</a>|C|
MAPLINK:
        default_human_gene|NAT1
NM:
        NM_000662|21361196|na
NP:
        NP_000653|4505335
OFFICIAL_GENE_NAME:
        N-acetyltransferase 1 (arylamine N-acetyltransferase)
OFFICIAL_SYMBOL:
        NAT1
OMIM:
        108345
ORGANISM:
        Homo sapiens
PMID:
        11955677,11955676,10908296,10862520,9168895,7773298,2340091
PREFERRED_PRODUCT:
        N-acetyltransferase 1
PRODUCT:
        N-acetyltransferase 1
STATUS:
        PROVISIONAL
STS:
            STS-D90041|8|57372|na|seq_map|epcr
            RH70671|8|63787|na|seq_map|epcr

SUMFUNC:
        Arylamine N-acetyltransferase 1; N- or O-acetylates arylamines and heterocyclic amines, detoxifies carcinogens and xenobiotics|Proteome
UNIGENE:
        Hs.155956
XM:
        NM_000662|21361196|na
XP:
        NP_000653|4505335|na


record 5

ACCNUM:
             ACCNUM:
                AF042740|2801806|na|na|na
             PROT:
                AAC03773|2801807
             TYPE:
                g

             ACCNUM:
                AF055874|3063613|na|na|na
             PROT:
                AAC14117|3063614
             TYPE:
                g

             ACCNUM:
                AF055875|3063615|na|na|na
             PROT:
                AAC14118|3063616
             TYPE:
                g

             ACCNUM:
                D10870|219871|na|na|na
             PROT:
                BAA01640|219872
             TYPE:
                g

             ACCNUM:
                D10871|219874|na|na|na
             PROT:
                BAA01641|219875
             TYPE:
                g

             ACCNUM:
                D10872|219877|na|na|na
             PROT:
                BAA01642|219878
             TYPE:
                g

             ACCNUM:
                M75163|189075|na|na|na
             PROT:
                AAA59906|553602
             TYPE:
                g

             ACCNUM:
                M75164|189072|na|na|na
             PROT:
                AAA59905|553601
             TYPE:
                g

             ACCNUM:
                U23052|747646|na|na|na
             PROT:
                AAA64584|727413
             TYPE:
                g

             ACCNUM:
                U23434|727456|na|na|na
             PROT:
                AAA64585|727457
             TYPE:
                g

             ACCNUM:
                U53473|1297331|na|na|na
             PROT:
                AAA98976|1297332
             TYPE:
                g

             ACCNUM:
                X14672|28227|na|na|na
             PROT:
                CAA32802|28228
             TYPE:
                g

             ACCNUM:
                BC015878|16198419|na|na|na
             PROT:
                AAH15878|16198420
             TYPE:
                m

             ACCNUM:
                D90040|219411|na|na|na
             PROT:
                BAA14094|219412
             TYPE:
                m

             ACCNUM:
                D90042|219415|na|na|na
             PROT:
                BAA14096|219416
             TYPE:
                m


ALIAS_PROT:
            Arylamine N-acetyltransferase-2
            arylamide acetylase 2 (N-acetyltransferase 2, isoniazid inactivation)

ALIAS_SYMBOL:
        AAC2
ASSEMBLY:
        D90042
CDD:
        N-acetyltransferase|pfam00797|838|na|3.274050e+02
CHR:
        8
COMP:
            10090|Nat2|8|8 31.00 cM|17961|8|NAT2|ncbi_mgd
            10090|Nat2|8|8 31.00 cM|17961|8|NAT2|ucsc_mgd

CONTIG:
        NT_030737.3|20541522|na|2088970|2098897|+|8
DB:
             DB_DESCR:
                GeneCards
             DB_LINK:
                http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?NAT2

             DB_DESCR:
                Arylamine N-Acetyltransferase Nomenclature
             DB_LINK:
                http://www.louisville.edu/medschool/pharmacology/NAT.html


ECNUM:
        2.3.1.5
EVID:
        supported by alignment with mRNA
EXTANNOT:
            cellular role|Other metabolism|E|Proteome|2340091
            biochemical function|Transferase|E|Proteome|2340091

GO:
        molecular function|arylamine N-acetyltransferase|E|GO:0004060|Proteome|2340091
GRIF:
            11846845|Association between bone loss in periodontal disease and polymorphism of N-acetyltransferase (NAT2)
            11915035|Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitis.
            12016157|urinary excretion of N(2)-(beta-1-glucos-iduronyl)-2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine relationship to activity levels of NAT2
            11872636|we investigated the relationship between the levels of aromatic DNA adducts in breast tissues and polymorphisms of the drug-metabolizing genes CYP1A1, NAT2, and GSTM1 in 166 women having breast cancer

LINK:
            http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=2
            http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?locusId=10
            http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=10[loc]
            http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:125365
            http://www.ensembl.org/Homo_sapiens/contigview?geneid=NM_000015
            http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg12&position=NM_000015
            http://mgc.nci.nih.gov/Genes/GeneInfo?ORG=Hs&CID=2

LOCUSID:
        10
LOCUS_CONFIRMED:
        yes
LOCUS_TYPE:
        gene with protein product, function known or inferred
MAP:
        8p22|<a href="http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:125365">HUGO</a>|C|
MAPLINK:
        default_human_gene|NAT2
NM:
        NM_000015|4557782|na
NP:
        NP_000006|4557783
OFFICIAL_GENE_NAME:
        N-acetyltransferase 2 (arylamine N-acetyltransferase)
OFFICIAL_SYMBOL:
        NAT2
OMIM:
        243400
ORGANISM:
        Homo sapiens
PMID:
        12016157,11915035,11872636,11846845,8460648,8102597,7915226,7773298,2734109,2340091,1968463,1676262,1381364,1306121
PREFERRED_PRODUCT:
        arylamide acetylase 2
PRODUCT:
        arylamide acetylase 2
STATUS:
        REVIEWED
STS:
            G06461|8|17088|na|seq_map|epcr
            WIAF-2120|8|44576|na|seq_map|epcr
            G59899|8|137181|na|seq_map|epcr
            GDB:187676|8|155563|na|seq_map|epcr
            GDB:310612|8|156422|na|seq_map|epcr
            GDB:310613|8|156423|na|seq_map|epcr
            GDB:386004|8|157141|na|seq_map|epcr

SUMFUNC:
        Arylamine N-acetyltransferase 2; N- or O-acetylates arylamines and heterocyclic amines|Proteome
SUMMARY:
        Summary: The intronless NAT2 gene encodes N-acetyltransferase 2 (arylamine N-acetyltransferase 2). This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid,intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity.A second arylamine N-acetyltransferase gene (NAT1) is located near NAT2.
UNIGENE:
        Hs.2
XM:
        NM_000015|4557782|na
XP:
        NP_000006|4557783|na


record 6

ALIAS_SYMBOL:
        NATP
DB:
             DB_DESCR:
                GeneCards
             DB_LINK:
                http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?AACP


LINK:
        http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:132838
LOCUSID:
        11
LOCUS_CONFIRMED:
        yes
LOCUS_TYPE:
        pseudogene
OFFICIAL_GENE_NAME:
        arylamide acetylase pseudogene
OFFICIAL_SYMBOL:
        AACP
ORGANISM:
        Homo sapiens
PMID:
        2340091


record 7

ACCNUM:
             ACCNUM:
                X00947|28331|na|na|na
             PROT:
                CAA25459|28332
             TYPE:
                g

             ACCNUM:
                X68733|439137|na|na|na
             PROT:
                CAA48671|1340142
             TYPE:
                g

             ACCNUM:
                AF089747|4165889|na|na|na
             PROT:
                AAD08810|4165890
             TYPE:
                m

             ACCNUM:
                BC003559|13097704|na|na|na
             PROT:
                AAH03559|13097705
             TYPE:
                m

             ACCNUM:
                J05176|177932|na|na|na
             PROT:
                AAA51560|177933
             TYPE:
                m

             ACCNUM:
                K01500|177808|na|na|na
             PROT:
                AAA51543|177809
             TYPE:
                m

             ACCNUM:
                M18906|177928|na|na|na
             PROT:
                AAA51559|177931
             TYPE:
                m


ALIAS_PROT:
            actichymotrypsin
            alpha-1-antichymotrypsin

ALIAS_SYMBOL:
            ACT
            AACT

ASSEMBLY:
        AH002551,K01500
CDD:
            SERine Proteinase INhibitors|SERPIN|950|na|3.744620e+02
            Serpins (serine protease inhibitors)|pfam00079|932|na|3.674510e+02
            Serpin (S protease inhibitor)|pfam00079|1225|5.273e-136|476.478
            SERine  Proteinase INhibitors|smart00093|1168|2.146e-129|454.521

CHR:
        14
COMP:
            10090|Pre2|12|12 52.00 cM|109636|14|SERPINA3|ucsc_mgd
            10090|X69832|12|12 957.87 cR|20717|14|AV689358|ucsc_est
            10090|AI194247|16|16 509.87 cR|16423|14|AW819120|ucsc_est

CONTIG:
        NT_026437.7|20543860|na|28765484|28777145|+|14
DB:
             DB_DESCR:
                GeneCards
             DB_LINK:
                http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?SERPINA3


EVID:
        supported by alignment with mRNA
EXTANNOT:
        biochemical function|Inhibitor or repressor|NR|Proteome|2404007
GO:
            molecular function|plasma protein|NR|GO:0005209|Proteome|na
            biological process|acute-phase response|NR|GO:0006953|Proteome|na
            molecular function|proteinase inhibitor|NR|GO:0004866|Proteome|na
            molecular function|serine protease inhibitor|E|GO:0004867|Proteome|2404007

GRIF:
            11959399|significantly higher in plasma of Alzheimer patients compared to controls
            11798857|A25G and G39A substitutions in the AACT gene are probably one of the risk factors to Alzheimer's disease (AD) in Han Chinese.

LINK:
            http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=234726
            http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?locusId=12
            http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=12[loc]
            http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:118955
            http://www.ensembl.org/Homo_sapiens/contigview?geneid=NM_001085
            http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg12&position=NM_001085
            http://mgc.nci.nih.gov/Genes/GeneInfo?ORG=Hs&CID=234726

LOCUSID:
        12
LOCUS_CONFIRMED:
        yes
LOCUS_TYPE:
        gene with protein product, function known or inferred
MAP:
        14q32.1|<a href="http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:118955">HUGO</a>|C|
MAPLINK:
        default_human_gene|SERPINA3
NM:
        NM_001085|9665246|na
NP:
        NP_001076|4501843
OFFICIAL_GENE_NAME:
        serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
OFFICIAL_SYMBOL:
        SERPINA3
OMIM:
        107280
ORGANISM:
        Homo sapiens
PHENOTYPE:
             PHENOTYPE:
                Alpha-1-antichymotrypsin deficiency
             PHENOTYPE_ID:
                107280

             PHENOTYPE:
                Cerebrovascular disease, occlusive
             PHENOTYPE_ID:
                107280


PMID:
        11959399,11798857,9880565,8244391,6687683,6606438,6556193,6547997,3492865,3485824,3260956,3257719,2404007,1351206
PREFERRED_PRODUCT:
        alpha-1-antichymotrypsin, precursor
PRODUCT:
        alpha-1-antichymotrypsin, precursor
STATUS:
        REVIEWED
STS:
            RH1625|14|32177|na|seq_map|epcr
            SHGC-32982|14|37467|na|na|epcr
            D14S845|14|64155|D14S845|seq_map|epcr
            G31126|14|66238|na|seq_map|epcr
            RH78280|14|74665|na|seq_map|epcr
            RH91507|14|86678|na|seq_map|epcr
            D14S1143|-|148321|D14S1143|na|epcr

SUMFUNC:
        Alpha-1-antichymotrypsin; member of the serpin family of serine protease inhibitors|Proteome
SUMMARY:
        Summary: The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class.  Polymorphisms in this protein appear to be tissue specific and influence protease targeting.  Variation in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease.  Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
UNIGENE:
        Hs.234726
XM:
        XM_028322|14748211|na
XP:
        XP_028322|14748212|na


record 8

ACCNUM:
             ACCNUM:
                L32179|537513|na|na|na
             PROT:
                AAA35551|537514
             TYPE:
                m


ALIAS_SYMBOL:
        DAC
ASSEMBLY:
        L32179
CDD:
            Carboxylesterases|pfam00135|154|na|6.439850e+01
            Carboxylesterase|pfam00135|137|7.185e-10|57.381

CHR:
        3
COMP:
            10090|Aadac|3|3  cM|67758|3|AADAC|ncbi_mgd
            10090|AI265437|3|3 5067.00 cR|67758|3|AA702448|natgen_paper

CONTIG:
        NT_005849.11|20537660|na|726090|740503|+|3
DB:
             DB_DESCR:
                GeneCards
             DB_LINK:
                http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?AADAC

             DB_DESCR:
                KEGG pathway: Butanoate metabolism
             DB_LINK:
                http://www.genome.ad.jp/dbget-bin/get_pathway?org_name=hsa&mapno=00650

             DB_DESCR:
                KEGG pathway: 2,4-Dichlorobenzoate degradation
             DB_LINK:
                http://www.genome.ad.jp/dbget-bin/get_pathway?org_name=hsa&mapno=00623

             DB_DESCR:
                KEGG pathway: Pentose and glucuronate interconversions
             DB_LINK:
                http://www.genome.ad.jp/dbget-bin/get_pathway?org_name=hsa&mapno=00040


ECNUM:
        3.1.1.-
EVID:
        supported by alignment with mRNA
EXTANNOT:
            cellular role|Other metabolism|P|Proteome|8063807
            subcellular localization|Microsomal fraction|NR|Proteome|8063807

GO:
            molecular function|enzyme|P|GO:0003824|Proteome|8063807
            cellular component|microsome|E|GO:0005792|Proteome|8063807

LINK:
            http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=587
            http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?locusId=13
            http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=13[loc]
            http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:392587
            http://www.ensembl.org/Homo_sapiens/contigview?geneid=NM_001086
            http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg12&position=NM_001086

LOCUSID:
        13
LOCUS_CONFIRMED:
        yes
LOCUS_TYPE:
        gene with protein product, function known or inferred
MAP:
        3q21.3-q25.2|RefSeq|C|
MAPLINK:
        default_human_gene|AADAC
NM:
        NM_001086|4557226|na
NP:
        NP_001077|4557227
OFFICIAL_GENE_NAME:
        arylacetamide deacetylase (esterase)
OFFICIAL_SYMBOL:
        AADAC
OMIM:
        600338
ORGANISM:
        Homo sapiens
PMID:
        9299245,8063807
PREFERRED_PRODUCT:
        arylacetamide deacetylase
PRODUCT:
        arylacetamide deacetylase
STATUS:
        REVIEWED
STS:
            STS-L32179|3|13170|na|seq_map|epcr
            D3S4189|-|18863|D3S4189|na|epcr
            RH36344|3|24707|na|seq_map|epcr
            RH124029|-|136046|na|na|epcr

SUMFUNC:
        Liver microsomal arylacetamide deacetylase; esterase involved in metabolically activating arylamine carcinogens|Proteome
SUMMARY:
        Summary: Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens
UNIGENE:
        Hs.587
XM:
        XM_003002|12729778|na
XP:
        XP_003002|11433103|na


record 9

ACCNUM:
             ACCNUM:
                BC020244|18044383|na|na|na
             PROT:
                AAH20244|18044384
             TYPE:
                m

             ACCNUM:
                M95627|870802|na|na|na
             PROT:
                AAA68889|870803
             TYPE:
                m


ASSEMBLY:
        M95627
CDD:
            WD40 repeats|smart00320|97|na|4.197260e+01
            WD domain, G-beta repeat|pfam00400|90|na|3.927620e+01

CHR:
        2
CONTIG:
        NT_005403.9|20537925|na|9668494|9674501|+|2
DB:
             DB_DESCR:
                GeneCards
             DB_LINK:
                http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?AAMP


EVID:
        supported by alignment with both mRNA and ESTs (3)
EXTANNOT:
            organismal role|Cell migration/motility|P|Proteome|7743515
            biochemical function|Adhesin/agglutinin|NR|Proteome|7743515

GO:
            biological process|cell motility|NR|GO:0006928|Proteome|na
            molecular function|heparin binding|P|GO:0008201|Proteome|7743515

LINK:
            http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=83347
            http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?locusId=14
            http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=14[loc]
            http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:4573993
            http://www.ensembl.org/Homo_sapiens/contigview?geneid=NM_001087
            http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg12&position=NM_001087

LOCUSID:
        14
LOCUS_CONFIRMED:
        yes
LOCUS_TYPE:
        gene with protein product, function known or inferred
MAP:
        2q36.1|RefSeq|C|
MAPLINK:
        default_human_gene|AAMP
NM:
        NM_001087|4557228|na
NP:
        NP_001078|4557229
OFFICIAL_GENE_NAME:
        angio-associated, migratory cell protein
OFFICIAL_SYMBOL:
        AAMP
OMIM:
        603488
ORGANISM:
        Homo sapiens
PMID:
        7743515
PREFERRED_PRODUCT:
        angio-associated, migratory cell protein
PRODUCT:
        angio-associated, migratory cell protein
STATUS:
        REVIEWED
STS:
        SGC31591|2|52581|na|seq_map|epcr
SUMFUNC:
        immunoglobulin-type protein; may mediate heparin-sensitive cell adhesion, may act in cell migration|Proteome
SUMMARY:
        Summary: The gene product is an immunoglobulin-type protein. It is found to be expressed strongly in endothelial cells, cytotrophoblasts, and poorly differentiated colon adenocarcinoma cells found in lymphatics. The protein contains a heparin-binding domain and mediates heparin-sensitive cell adhesion.
UNIGENE:
        Hs.83347
XM:
        NM_001087|4557228|na
XP:
        NP_001078|4557229|na




