METATOOL OUTPUT Version 3.5 (28.03.2001) C:\METATOOL\META35~1.EXE

INPUT FILE: EXAMPLE14.TXT

INTERNAL METABOLITES: 13
REACTIONS: 5

  2 external H2O
  1 int      5,6,7,8-Tetrahydrofolate
  1 int      NADP+
  1 int      7,8-dihydrofolate
  1 int      NADPH
  1 int      An_orthophosphoric_monoester
  1 int      an_alcohol
  1 int      phosphate
  1 int      GTP
  1 int      formate
  1 int      2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine_triphosphate
  1 int      6-(L-erythro-1,2-Dihydroxypropyl_3-triphosphate)-7,8-dihydropterin
  1 int      6-(1,2-dioxopropyl)-5,6,7,8-tetrahydropterin
  1 int      triphosphate
 14 metabolites,  15 is the summarized frequency

edges	frequency of nodes
  0	  0
  1	 13
  2	  1

STOICHIOMETRIC MATRIX
 
 matrix dimension r13 x c5
-1  0  0  0  0 
-1  0  0  0  0 
 1  0  0  0  0 
 1  0  0  0  0 
 0  0 -1  0  0 
 0  0  1  0  0 
 0  0  1  0  0 
 0  0  0 -1  0 
 0  0  0  1  0 
 0  0  0  1  0 
 0  0  0  0 -1 
 0  0  0  0  1 
 0  0  0  0  1 
The following line indicates reversible (0) and irreversible reactions (1)
 0  1  1  1  1 
rows and columns are sorted as declared in the inputfile

NOT BALANCED INTERNAL METABOLITES
5,6,7,8-Tetrahydrofolate	NADP+	7,8-dihydrofolate	NADPH	An_orthophosphoric_monoester	an_alcohol	phosphate	GTP	formate	2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine_triphosphate	6-(L-erythro-1,2-Dihydroxypropyl_3-triphosphate)-7,8-dihydropterin	6-(1,2-dioxopropyl)-5,6,7,8-tetrahydropterin	triphosphate	

KERNEL
 
 matrix dimension r1 x c5
 0  1  0  0  0 
5 reactions (columns) are sorted in the same order as in the ENZREV ENZIRREV section.

 enzymes

 1:	 1.5.1.3 irreversible

 overall reaction
 - not found -


The remaining overall reactions perform no net transformation of external metabolites.

SUBSETS OF REACTIONS
 
 matrix dimension r1 x c5
 0  1  0  0  0 
5 reactions (columns) are sorted in the same order as in the ENZREV ENZIRREV section.

 enzymes

 1:	 1.5.1.3 irreversible

 overall reaction
 - not found -


The remaining overall reactions perform no net transformation of external metabolites.

REDUCED SYSTEM with 13 branch point metabolites in 1 reactions (columns)
 
 matrix dimension r0 x c1
The following line indicates reversible (0) and irreversible reactions (1)
 1 

-> Branch metabolites are : 
met                 	cons	built	reactions

-> No branch metabolites are : 
met                 	cons	built	reactions
5,6,7,8-Tetrahydrofolate	1	0	1	r
NADP+               	1	0	1	r
7,8-dihydrofolate   	0	1	1	r
NADPH               	0	1	1	r
An_orthophosphoric_monoester	1	0	1	i
an_alcohol          	0	1	1	i
phosphate           	0	1	1	i
GTP                 	1	0	1	i
formate             	0	1	1	i
2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine_triphosphate	0	1	1	i
6-(L-erythro-1,2-Dihydroxypropyl_3-triphosphate)-7,8-dihydropterin	1	0	1	i
6-(1,2-dioxopropyl)-5,6,7,8-tetrahydropterin	0	1	1	i
triphosphate        	0	1	1	i

CONVEX BASIS
 
 matrix dimension r1 x c5
 0  1  0  0  0 

 enzymes

 1:	 1.5.1.3 irreversible

 overall reaction
 - not found -


The remaining overall reactions perform no net transformation of external metabolites.

CONSERVATION RELATIONS
 
 matrix dimension r9 x c13
 1 -1  0  0  0  0  0  0  0  0  0  0  0 
 1  0  1  0  0  0  0  0  0  0  0  0  0 
 1  0  0  1  0  0  0  0  0  0  0  0  0 
 0  0  0  0  1  1  0  0  0  0  0  0  0 
 0  0  0  0  1  0  1  0  0  0  0  0  0 
 0  0  0  0  0  0  0  1  1  0  0  0  0 
 0  0  0  0  0  0  0  1  0  1  0  0  0 
 0  0  0  0  0  0  0  0  0  0  1  1  0 
 0  0  0  0  0  0  0  0  0  0  1  0  1 
 1 :	5,6,7,8-Tetrahydrofolate + NADP+ = const
 2 :	5,6,7,8-Tetrahydrofolate + 7,8-dihydrofolate = const
 3 :	5,6,7,8-Tetrahydrofolate + NADPH = const
 4 :	An_orthophosphoric_monoester + an_alcohol = const
 5 :	An_orthophosphoric_monoester + phosphate = const
 6 :	GTP + formate = const
 7 :	GTP + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine_triphosphate = const
 8 :	6-(L-erythro-1,2-Dihydroxypropyl_3-triphosphate)-7,8-dihydropterin + 6-(1,2-dioxopropyl)-5,6,7,8-tetrahydropterin = const
 9 :	6-(L-erythro-1,2-Dihydroxypropyl_3-triphosphate)-7,8-dihydropterin + triphosphate = const

ELEMENTARY MODES
 
 matrix dimension r1 x c5
 0  1  0  0  0 
5 reactions (columns) are sorted in the same order as in the ENZREV ENZIRREV section.

 enzymes

 1:	 1.5.1.3 irreversible

 overall reaction
 - not found -


The remaining overall reactions perform no net transformation of external metabolites.

The elementary modes ARE EQUAL to convex basis.
