R03591:1.1.1.218: Morphine + NAD+ <=> Morphinone + NADH
R03592:1.1.1.218: Morphine + NADP+ <=> Morphinone + NADPH
R05124:1.1.1.247: Codeinone + NADPH <=> Codeine + NADP+
R04697:1.1.1.248: Salutaridine + NADPH <=> Salutaridinol + NADP+
R00044:1.1.3.26: 2 Columbamine + O2 <=>  2 Berberine + 2 H2O
R04690:1.1.3.32: (S)-Cheilanthifoline + NADPH + O2 <=> (S)-Stylopine + NADP+ + 2 H2O
R03834:1.1.3.33: (S)-Scoulerine + NADPH + O2 <=> (S)-Cheilanthifoline + NADP+ + 2 H2O 
R04694:1.1.3.34: (R)-N-Methylcoclaurine + (S)-N-Methylcoclaurine + NADPH + O2 <=> Berbamunine + NADP + 2 H2O
R05215:1.1.3.34: 2 (R)-N-Methylcoclaurine + NADPH + O2 <=> Guattegaumerine + NADP + 2 H2O
R05210:1.1.3.34: (R)-N-Methylcoclaurine + (S)-Coclaurine + NADPH + O2 <=> 2'-Norberbamunine  + NADP + 2 H2O
R04696:1.1.3.35: (R)-Reticuline + NADPH + O2 <=> Salutaridine + NADP+ + 2 H2O
R04400:1.1.3.36: (S)-Tetrahydrocolumbamine + NADPH + O2 <=> (S)-Canadine + NADP+ + 2 H2O
R03722:1.3.3.8: (S)-Tetrahydrocolumbamine + 2 O2 <=> Columbamine + 2 H2O2
R02880:1.3.3.8: (S)-Canadine + 2 O2 <=> Berberine + 2 H2O2
R00729:1.4.3.2: L-Tyrosine + H2O + O2 <=> 4-Hydroxyphenylpyruvate + NH3 + H2O2
R04695:1.5.1.27: 1,2-Dehydroreticuline + NADPH <=> (R)-Reticuline + NADP+
R03831:1.5.3.9: (S)-Reticuline + O2 <=> (S)-Scoulerine + H2O2
R04703:1.5.3.12: Dihydrosanguinarine + O2 <=> Sanguinarine + H2O2
R04768:1.5.3.12: Dihydromacarpine + O2 <=> Macarpine + H2O2
R04706:1.5.3.12: Dihydrochelirubine + O2 <=> Chelirubine + H2O2
R04699:1.14.13.55: Protopine + NADPH + O2 <=> 6-Hydroxyprotopine + NADP+ + H2O
R04702:1.14.13.56: Dihydrosanguinarine + NADPH + O2 <=> 10-Hydroxydihydrosanguinarine + NADP+ + H2O
R04708:1.14.13.57: Dihydrochelirubine <=> 12-Hydroxychelirubine
R02386:1.14.18.1: Tyramine <=> Dopamine
R04693:1.14.18.1: (S)-N-Methylcoclaurine <=> (S)-3'-Hydroxy-N-methylcoclaurine
R04077:2.1.1.89: S-Adenosyl-L-methionine + (S)-Tetrahydrocolumbamine <=> S-Adenosyl-L-homocysteine + Tetrahydropalmatine
R05216:2.1.1.115: S-Adenosyl-L-methionine + (R)-Norreticuline <=> S-Adenosyl-L-homocysteine + (R)-Reticuline
R04692:2.1.1.115: S-Adenosyl-L-methionine + (S)-Coclaurine <=> S-Adenosyl-L-homocysteine + (S)-N-Methylcoclaurine 
R05211:2.1.1.115: S-Adenosyl-L-methionine + (S)-Norreticuline <=> S-Adenosyl-L-homocysteine + (S)-Reticuline
R03832:2.1.1.116: S-Adenosyl-L-methionine + 3'-Hydroxy-N-methyl-(S)-coclaurine <=> S-Adenosyl-L-homocysteine + (S)-Reticuline
R05212:2.1.1.116: S-Adenosyl-L-methionine + (S)-3'-Hydroxycoclaurine <=> S-Adenosyl-L-homocysteine + (S)-Norreticuline
R03835:2.1.1.117: S-Adenosyl-L-methionine + (S)-Scoulerine <=> S-Adenosyl-L-homocysteine + (S)-Tetrahydrocolumbamine
R03721:2.1.1.118: S-Adenosyl-L-methionine + Columbamine <=> S-Adenosyl-L-homocysteine + Palmatine
R04707:2.1.1.119: S-Adenosyl-L-methionine + 10-Hydroxydihydrosanguinarine <=> S-Adenosyl-L-homocysteine + Dihydrochelirubine
R04705:2.1.1.120: S-Adenosyl-L-methionine + 12-Hydroxydihydrochelirubine <=> S-Adenosyl-L-homocysteine + Dihydromacarpine
R05213:2.1.1.121: S-Adenosyl-L-methionine + (S)-6-O-Methylnorlaudanosoline <=> S-Adenosyl-L-homocysteine + (S)-Nororientaline
R05123:2.1.1.128: S-Adenosyl-L-methionine + (S)-Norcoclaurine <=> S-Adenosyl-L-homocysteine + (S)-Coclaurine
R05214:2.1.1.128: S-Adenosyl-L-methionine + (S)-Norlaudanosoline <=> S-Adenosyl-L-homocysteine + (S)-6-O-Methylnorlaudanosoline
R04723:2.3.1.150: Acetyl-CoA + Salutaridinol <=> CoA + 7-O-Acetylsalutaridinol
R00734:2.6.1.1: L-Tyrosine + 2-Oxoglutarate <=> 4-Hydroxyphenylpyruvate + L-Glutamate
R00734:2.6.1.5: L-Tyrosine + 2-Oxoglutarate <=> 3-(4-Hydroxyphenyl)pyruvate + L-Glutamate
R00734:2.6.1.57: L-Tyrosine + 2-Oxoglutarate <=> 4-Hydroxyphenylpyruvate + L-Glutamate
R00736:4.1.1.25: L-Tyrosine <=> Tyramine + CO2
R00736:4.1.1.28: L-Tyrosine <=> Tyramine + CO2
R04700:1.14.13.-: (S)-cis-N-methylstylopine <=> Protopine
R03341:4.1.1.-: 4-Hydroxyphenylpyruvate <=> 4-Hydroxyphenylacetaldehyde + CO2
R04305:4.2.1.78: Dopamine + 4-Hydroxyphenylacetaldehyde <=> (S)-Norcoclaurine + H2O
R04084:4.2.1.78: Dopamine + 3,4-Dihydroxyphenylacetaldehyde <=> (S)-Norlaudanosoline + H2O
R04691:0.0.0.0: (S)-Stylopine + S-Adenosyl-L-methionine <=> (S)-cis-N-methylstylopine
R04701:0.0.0.0: 6-Hydroxyprotopine <=> Dihydrosanguinarine
R04769:0.0.0.0: Salutaridinol acetate <=> Thebaine
R05126:0.0.0.0: Thebaine <=> Neopinone
R05125:0.0.0.0: Neopinone <=> Codeinone
R05127:0.0.0.0: Thebaine <=> Oripavine
R03698:0.0.0.0: Oripavine <=> Morphinone
R03697:0.0.0.0: Morphinone <=> Codeine
